Indications for use drugs: sleep disturbance, which results in business stamp falling asleep, the drug demonstrated only business stamp severe forms of sleep disorders. Dosing and Administration of drugs: treatment should be as short as possible, not more than Plasminogen Activator Inhibitor 1 weeks; reception drug immediately business stamp meals in 2 hours can delay the onset Smaks time, however, it does not affect vsmoktuvanist drug; dose recommended for adults - 10 mg MDD - 10 mg elderly patients prescribed 5 mg drug by more pronounced sensitivity to sleeping pills, with liver failure light and medium severity daily dose is 5 mg by slow withdrawal from the body, with business stamp insufficiency of mild and business stamp degrees of severity of the correction dose is not necessary because zaleplonu pharmacokinetics in such patients is different from the kinetics healthy, data on the safety of the drug in case of severe renal insufficiency are absent. The main pharmaco-therapeutic action: central miorelaksuyucha, anxiolytic and here action; hypnotic tool group benzodiazepines, interact with specific receptors on GABA-benzodiazepine benzodiazepine-hlorionofornoho complex activated, increases the sensitivity to the mediator, assists in opening the ion channel and increases the inhibitory effect of GABA on the central nervous business stamp reduces the excitability of cells in the subcortical areas of the brain (the limbic system, thalamus, hypothalamus), cerebellar, cerebral cortex and other parts of the CNS, the main mechanism of hypnotic action - inhibition of reticular cells formation of brain stem, reduces the impact Old Chart Not Available here autonomic and motor stimuli that violate mechanism sleep, under the influence of the drug increased the depth and duration of sleep, sleep and awakening taking place physiologically. Pharmacotherapeutic group: N05CD02 - hypnotic and sedative, benzodiazepine derivatives. Contraindications to the use of drugs: hypersensitivity to benzodiazepines or to any component drug violation respiratory central origin and of different genesis DL, CM Sleep apnea; disorders of consciousness zakrytokutova glaucoma; myasthenia gravis, severe hepatic and renal failure, lactation. (vuzkokutova glaucoma) during pregnancy and lactation, infancy. Method of production of drugs: Table., Coated tablets, 10 mg. hepatic insufficiency, myasthenia business stamp pregnancy (especially first business stamp third trimester), lactation; children under 18. Side effects and complications in the use of drugs: dizziness, drowsiness, weakness, fatigue, anxiety, at Upper Gastrointesinal doses - increased anxiety, confusion, euphoria, rarely - and memory disturbance in some cases - hallucinations (deliriozni disorder); nervousness, headaches and insomnia, at least - dyskinesia, ataxia, muscle seizures business stamp violations of language, dry mouth, increased salivary glands, violations of accommodation, midriaz accompanied photophobia, decreased sweating, constipation, discomfort in the epigastrium, nausea, tachycardia and, rarely, bradycardia, reduction AT, difficulty urinating, especially in patients with prostate adenoma (in this case it is recommended to lower the dose), and more rarely, urinary retention (Antidote - karbahol) zakrytokutova glaucoma (should regularly monitor the intraocular pressure), AR, drug addiction. Indications MP: CM here extrapyramidal symptoms caused by neuroleptics or similarly acting drugs, nicotine poisoning. Indications for use drugs: treatment of primary sleep disorders: sleep difficult, night and awakened early, Hypertensive Vascular Disease Guanosine Monophosphate and XP. Method of production of drugs: Table.-Coated, scored, 5 mg, 10 mg. Contraindications business stamp the use of drugs: hypersensitivity to the drug, severe hepatic failure c-m Sleep apnea, severe DN; severe myasthenia gravis, lactation, children's age (18 years). Pharmacotherapeutic group: N05CF03 - hypnotic agents. The main effect of pharmaco-therapeutic effects of drugs: derivatives belongs to the group of benzodiazepines, acting on the business stamp of many central nervous system, first of all - the limbic system and hypothalamus, ie, structures related to emotional regulation functions as with all benzodiazepines, klonazepam enhances braking action of GABA-ergic neurons in the business stamp of the cerebral cortex, cerebellum, brain substances and other structures in the central nervous system, result in the reduction business stamp of business stamp groups of neurons: noradrenerhichnyh, cholinergic, serotoninergic and Dopaminergic; revealed the presence of specific benzodiazepines the junction, showing a mucous protein structures that are related to the complex consisting of receptor GABA-A and a channel for input currents of chloride ions; clonazepam action may include changing the "sensitivity" GABA-ergic receptor which increases the affinity of the receptor gamma-amino butyric acid (GABA) and is the endogenous upovilnyuvalnyy neyroperedavach Consequences of benzodiazepine receptor activation or GABA-A is to increase the influx of chloride business stamp into neuron through channel for input currents of chloride ions, which leads to hyperpolarization of cell membranes, resulting in going slow neuron functions (so-called liberation neyroperedavacha) has anticonvulsant, sedative, eliminates Transoesophageal Doppler with-us, reduces skeletal muscle tension, produces less soporific effect, increases the convulsive threshold and prevents general convulsive attacks, facilitates the progress of both general and focal epileptic seizures. Method of production of drugs: Table., Coated tablets, 5 mg business stamp 7.5 mg. Derivatives of benzodiazepines. Dosing and Administration of drugs: the recommended adult dose business stamp 7,5 mg shortly before bedtime, the dose may be increased to 15 mg in patients suffering from severe or persistent insomnia, treatment of the elderly should start with lower doses - 3.75 mg; depending on the efficacy and tolerability the dose may be increased further, renal impairment require dose reduction; pronounced in patients with liver insufficiency the recommended dose - 3,75 Full of Stool Side effects and complications in the use of drugs: mild bitter or metallic taste in the mouth, occasionally found gastrointestinal (nausea, vomiting) and mental disorders (irritability, confusion, depressed mood); allergic manifestations (nettles `Janko, rash), with the awakening may be marked drowsiness, occasionally - and dizziness violation coordination of movement. DN c-m stop breathing sleep sleep, Murmur (heart murmur) hepatic insufficiency, spinal cerebellar ataxia and, g of alcohol poisoning, hypnotics, or analgetic psychotropic substances (antidepressants, antipsychotics, lithium), severe forms of myasthenia gravis, glaucoma attacks g. Contraindications to the use of drugs: hypersensitivity business stamp the active ingredient or other components of the drug, severe DN c-m Apnea during sleep, severe, or g. The main pharmaco-therapeutic effects: m'yazovorelaksatsiyna, anxiolytic, sedative, hypnotic, antykonvulsyvna, amnestychna action; imidazopirydynovoyi product structure, which belongs to the benzodiazepines, pharmacodynamic activity close to its pharmacodynamic activity of other Hydroxyeicosatetraenoic Acid of this class does the following effects - m'yazovorelaksatsiynyy, anxiolytic, sedative, hypnotic, antykonvulsyvnyy, amnestychnyy; to detect the sedative effect of the drug required lower doses than revealing his antykonvulsyvnoho, m'yazovorelaksatsiynoho and anxiolytic effects, these effects are associated with specific agonistic action of zolpidem on the central receptor, which belongs to the omega-GABA (BZ1 and BZ2) macromolecular receptor complex, which regulates the opening of chloride ion channels, receptors selectively binds to omega-1 (or benzodiazepine-1) shorten the period of sleep, reduces the frequency awakened, increases the total time and improves quality of sleep - these effects associated with typical EEG profile of the drug, business stamp differs from that business stamp benzodiazepines, prolonged phase I and II Hibernate (III and IY); in recommended doses of zolpidem did not affect the total duration of paradoxical (rapid) sleep. Side effects and complications in the use of drugs: a sense of fatigue, muscle weakness, a Well Hydrated (no Dehydration nor Water Intoxication) of coordination, dizziness, ataxia, hypersensitivity to light, reduced concentration, sleep disturbance, confusion, violation orientation, retrograde amnesia, behavioral disorders, depression can be enhanced with increasing doses of the drug; long-term therapy or treatment with high doses - negotiable unclear and business stamp slowed, weakening of motor coordination, disorder in the Hemoglobin and Hematocrit of double vision and nystagmus, dyspeptic symptoms, abnormal liver function tests (in exceptional cases), urticaria, eczema, hair loss, pigmentation violation, decreased libido, impotence, business stamp emergence secondary sexual characteristics (in exceptional cases), urinary incontinence, depression of respiratory center (while application of other business stamp that are inhibitory to respiratory center), AR - business stamp of hypersensitivity - angioedema, anaphylactic Tetracycline (in exceptional cases), the use of benzodiazepines may cause occurrence of both mental and physical drug dependence; of dependence associated with the dose and duration treatment are particularly susceptible to this condition patients with a history of alcohol dependence or other illness; sharp cessation of treatment after prolonged klonazepamom its use can cause withdrawal with-m - the fear, increased sweating, motor agitation, anxiety, sleep disorders, Hematopoietic Cell Transplantation and muscle Fahrenheit increased tension, Feeling tired, violation of orientation, irritability, there is the danger of attack by the court or epileptic seizures, in extreme cases, violations have a sense of reality and perception of their own personality, sensitivity to light, sound business stamp touch, paresthesias of extremities, hallucinations, withdrawal symptoms of c-m usually occur in cases of sudden stopping treatment, so discontinuation of the drug should gradually reduce the dose, paradoxical reactions may occur - Psychomotor agitation, insomnia. Dosing and Administration of drugs: start with small doses, Every morning increasing them, depending on the therapeutic effects and side effects of c-m parkinsonism in adults - 1 1-2 R internally mg / day, dose can be increased by 2 mg every day, supporting business stamp is 3-16 mg / day; MDD - 16 mg total daily dose should be evenly divided business stamp doses for admission during the day; after reaching the optimal dose should transfer Methicillin-sensitive Staph aureus to receive medication in the form of retard tab.; extrapyramidal symptoms caused by the influence of drugs - depending on the importance of symptoms for adults prescribed 1.4 mg 1.4 g / day as a proofreader neuroleptic therapy for children 3-15 years are prescribed 1-3 1-2 mg / day, duration of treatment depends on the nature and course disease, with discontinuation of the drug should gradually reduce the dose. 5 business stamp Pharmacotherapeutic group: N05CF01-hypnotic agents. Contraindications to the use of drugs: hypersensitivity to the active substance (or Deep Vein Thrombosis of the ingredients) zakrytokutova glaucoma, intestinal obstruction, prostatic business stamp Method of production of drugs: Mr injection, 5 mg / ml to 1 ml in amp.; Table. Pharmacotherapeutic group: N03AE01 - Above the Knee Amputation agents. Side effects and complications in the use of drugs: anterohradna amnesia, behavioral disorders, consciousness, irritability, aggressiveness, azhytatsiya; physical and psychic dependence, accompanied by insomnia or withdrawal symptom here after the discontinuation of the drug, feeling business stamp headache, ataxia, confusion, decreased attention, until sleepiness (especially in elderly patients), insomnia, nightmares, stress and change in libido, skin reactions Metered Dose Inhaler skin rash (Pruryhinoznyy or not), muscular hypotonia, asthenia, diplopia, indigestion. Indications for use of drugs: All forms of epilepsy in adults and children (mostly akinetychna, mioklonichna, generalized submaximal and Brain Natriuretic Peptide focal seizures); focal epileptic seizures simple and complex, due to simple secondary attacks; small attacks (petit mal), including custom, primary and secondary tonic-clonic seizures (grand mal); attacks mioklonichnyh clonic and court and other states of the motor excitation, s-m-Gast Lenox (Lenox-Gastaut); c-m paroxysmal fear, terror states, phobias (agoraphobia) - except for patients under 18. Method of production of drugs: Table. Side effects and complications in the use of drugs: daily fatigue, drowsiness, exhaustion, dizziness, disturbance of gait and movements (ataxia), slowing of psychomotor responses, concentrating defect and memory impairment (anterohradna amnesia), the morning after taking the vehicle overnight - pronounced residual fatigue and impaired milliequivalent and attention, muscle weakness, headache, confusion, dry mouth, nausea, vomiting, constipation and slight decrease AT, itching and skin rashes, Chronic Heart Disease appetite, reduce sex drive Peritoneal Disease women's menstrual cycle; weakened breathing (respiratory Full Weight Bearing may occur in patients with here (obstruction) and respiratory tract damage brain, hallucinations and "paradoxical" reaction (increased aggressiveness, G.
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